It's actually a bit simpler in some respects and a little more complex in another.
As for simpler, you're of course only dealing with the one file. You don't have to set up the import routine.
As for more difficult, and only slightly so, you do need the Workgroup Manager which is a download from Windchill. Unlike Editor, the connection to browse/search Windchill is not build directly into IsoDraw. Once you install the manager (downloads from inside Windchill) it basically just acts as a separate window.
So, in our situation, when someone starts IsoDraw it automatically kicks off Workgroup Manager. From the manager you can check-out/in a file. There's also a quick view button (depending on your WC version). This opens it directly in IsoDraw. It does not check-out the file though. If modifications are made and you attempt to save it will note this and ask if you want to check it out.
Works pretty well. As a side note, this does connect IsoDraw and Windchill even more so in regards to upgrades. The IsoDraw version must be compatible with the Windchill version in place. Not too surprising there. You can also then place your Creo files (assuming you are using) directly into the IsoDraw files and the relationship is maintained.